Answer:
there is a slight distinction, and what you refer to is actually not "to empty a room" but "to empty out a room".
If someone said to me that they were "to empty a room", I would think that a room was crowded with people and all the people left. A bad comedian can empty a room, an unpleasant smell can also. To then take all the furniture out would be to empty out the room.
Explanation:
